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Brain Natriuretic Peptide (BNP)  (BNP)

Synonyms:  BNP, NT proBNP
Specimen:  Blood; (1) Green (lithium heparin) top vacutainer tube ONLY.
                        Volume:  Full primary tube
Minimum Volume:  0.5 ml whole blood or plasma
Collection:  Transfer plasma to a tightly capped plastic aliquot tube within 2 hours of collection if testing is delayed. Maintain specimen at 20-35°C or refrigerate at 2-8°C for 3 days; freeze at -20°C for 12 months.
Rejection Criteria:  Serum or EDTA samples; improper labeling.
Reference Range:  Clinically Reportable Range (CRR): 30-175,000 pg/mL
Methodology:  Chemiluminescent immunoassay
Test Use:  In individuals suspected of having congestive heart failure (CHF), measurements of NT-proBNP are used as an aid in the diagnosis and assessment of severity. The test is further indicated for the risk stratification of patients with acute coronary syndrom
Additional Information:  Repetitive freezing and thawing of specimens should be avoided.
Testing Includes:  Quantitative measurement of N-terminal pro-brain natriuretic peptide (NT-proBNP)
Testing Facility:  AnMed Health Laboratory