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Alpha-Fetoprotein (AFP), Serum, Tumor Marker  (AFP TM)

Synonyms:  AFP, Alpha I - Fetoprotein
Specimen:  Blood; (1) SST (serum separator) or Red (no preservative) top vacutainer tube.
                        Volume:  Full primary tube
Minimum Volume:  0.3 mL serum
Collection:  If tube other than an SST is collected, transfer serum to a tightly capped plastic aliquot tube within 2 hours of collection for transport. Refrigerate at 2-8°C.
Storage:  Refrigerate at 2-8 degrees C
Rejection Criteria:  Gross hemolysis; plasma specimen; improper labeling.
Reference Range:  Tumor marker nomrals: 0-6.0 ng/mL Normal values apply only to males and nonpregnant females.
Methodology:  Immunochemiluminometric assay (ICMA)
Test Use:  The most important application of AFP testing in cancer management is for testicular cancer. Although not present in pure seminoma,1 elevated serum AFP is closely associated with nonseminomatous testicular cancer.2-4 The measurement of AFP in serum, in co
Additional Information:  In adults, serum AFP concentrations remain low except during pregnancy, benign liver diseases, (hepatitis, cirrhosis), primary hepatocellular carcinoma, and certain germ cell tumors.
Testing Includes:  Specimen sent to LabCorp. LabCorp test # 002253.
Testing Facility:  LabCorp