| Synonyms:
| Progressive ANA Follow up testing |
| Specimen: | Blood; 1) SST (serum separator) or Red (no preservative) top vacutainer tube. |
| Volume: | Full primary tube |
| Minimum Volume: | 2 mL serum |
| Collection: | If tube other than an SST is collected, transfer serum to a tightly capped plastic aliquot tube within 2 hours of collection for transport.
Refrigerate at 2-8°C for 7 days. |
| Rejection Criteria: | Lipemia; gross bacterial contamination; improper labeling. |
| Reference Range: | Anti-ds-DNA: Negative: 0-29-IU/mLAnti-histone: Negative: <20 units/mLAnti-Sm: Negative: <20 units/mLAnti-RNP: Negative: <20 units/mLAnti-SSA: Negative < 20 units/mLAnti-SSB: Negative < 20 units/mLAnti-SCL-70: Negative < 20 units/mL |
| Methodology: | Enzyme Immunoassay (EIA) |
| Test Use: | Determination of specific antibody results as follow up to positive antinuclear antibody testing or as requested by clinician. |
| Additional Information: | Performed when Progressive ANA is requested and result of ANA meets criteria for follow up testing. |
| Testing Includes: | Anti-DS-DNA, Anti-extractable nuclear antigen, RNP, RA Factor, anti-histone, anti-SSA, anti-SSB, and anti-SCL70.
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| Testing Facility: | LabCorp |