Leukemia/Lymphoma, Chromosome Analysis (CYTOGEN)
|
| Synonyms:
| Chromosome Analysis, Hematologic Disorders, Philadelphia Chromosome |
| Specimen: | Bone Marrow, blood, lymph node, spleen, bone core, or effusion.
It is best if bone marrow specimens are obtained Monday through Sunday from 7:00 am to 3:00 pm. After 3:00 pm, bone marrows must be scheduled in order to provide coverage. Patient should not be on chemotherapy. |
| Volume: | 2 mL bone marrow, 3 mL peripheral blood, or 0.5-1 mL tissue biopsy. |
| Minimum Volume: | |
| Collection: | Bone marrow or peripheral blood in pediatric Green (heparin) tube; lymph node, spleen, bone core, CSF, or effusion in lymph node transport bottle.
Specimens should arrive in the testing laboratory within 48 hours of collection.
Maintain specimen at room temperature.
|
| Rejection Criteria: | Hemolysis; gross contamination; no immature cells; clotted specimen; frozen specimen; fixed specimen; use of incorrect or too much anticoagulant; improper labeling. |
| Reference Range: | See report |
| Methodology: | Short-term cell culture; synchronization; chromosome harvest; G-banding; analysis (20 metaphases) and karyotyping; long-term β-mitogen cultures in some B-cell leukemias. |
| Test Use: | Identify specific chromosome abnormalities associated with chronic and acute leukemia and lymphoma, as well as myelodysplasia. |
| Additional Information: | It is best if bone marrow specimens are obtained Monday through Sunday from 7:00 am to 2:30 pm. After 5:00 pm, bone marrows must be scheduled in order to provide coverage. Patient should not be on chemotherapy. |
| Testing Includes: | Specimen sent to US Labs. |
| Testing Facility: | LabCorp to US Labs |