AnMed Laboratory Services

         

Dexamethasone Suppression (Cushings)  (DEXA SUP CS)

Synonyms:  None listed
Specimen:  Blood; (1) SST (serum separator) or Red (no preservative) top vacutainer tube. On Day 1, patient has cortisol levels drawn at 0800 and 1600. A 1 mg dose of dexamethasone is administered at 2300 on Day 1. On Day 2 An additional cortisol level is drawn at 0800.
                        Volume:  Full primary tube
Minimum Volume:  200 microL serum
Collection:  Outpatients must be scheduled through First Call at (864)512-2255. To schedule Inpatients, call extension 1377. If tube other than an SST (serum separator) is collected, transfer serum to a tightly capped plastic aliquot tube within 2 hours of collection for transport. Refrigerate at 2-8°C for 7 days.
Rejection Criteria:  improper labeling
Reference Range:  After the administration of 1 mg of dexamethasone at 11 pm, normal individuals will typically have a cortisol level of less than 5 mcg/dL at 8 am the following morning. In the presence of Cushings, the cortisol level is greater than 10 mcg/dL. While thi
Methodology: 
Test Use:  Tool used for diagnosing Cushings Syndrome.
Additional Information: 
Testing Includes:  Day 1: 0800 and 1600 Cortisol; 1 mg Dexamethasone is given at 2300. Day 2: 0800 Cortisol.
Testing Facility:  AnMed Laboratory